Press conference in Q4 of 2026: the launch of the MOVE website and the publication of our commissioned research. Media only. Event details

Research

The Evidence Library

On harm reduction, nicotine without smoke, the latest Cochrane review, and more.

Last reviewed 23 October 2026.

One

Our own research

  1. Forthcoming

    Malaysia’s Vape Ban: At the crossroads of public health and the black market

    Expected late 2026.

    MOVE commissioned an independent study examining the consequences of a vape ban for public health, product regulation and the illicit market in Malaysia. We will publish a summary of its findings.

Two

Harm Reduction: Systematic Reviews and Meta-analyses

  1. Systematic review Living review

    Electronic cigarettes for smoking cessation

    Cochrane Library. Living review, current version pub11, published 26 August 2026, with evidence current to 1 January 2026. DOI 10.1002/14651858.CD010216.pub11. Cochrane’s plain-language summary · free full text of the current version, pub11.

    High-certainty evidence that nicotine e-cigarettes help more people stop smoking than traditional nicotine replacement therapy. A living review that is updated as new trials appear.

    It is about smoking cessation among adults who already smoke. It says nothing about people who never smoked, nothing about young people, and nothing about long-term harm. It reports short-term side effects, but it is not a long-term safety study.

  2. Meta-analysis

    Efficacy and safety of e-cigarette use for smoking cessation: a systematic review and meta-analysis of randomised controlled trials

    PubMed 37148992, 2023.

    Pools randomised controlled trials on cessation efficacy and reported safety outcomes. Sits alongside the Cochrane review as independent confirmation from a separate research team.

    Trial follow-up periods are short relative to the timescale on which smoking-related disease develops. Efficacy at six or twelve months is not a statement about twenty years.

  3. Randomised trial

    Effect of unguided e-cigarette provision on uptake, use, and smoking cessation among adults who smoke in the USA: a naturalistic, randomised, controlled clinical trial

    Carpenter and colleagues, MUSC Hollings Cancer Center, eClinicalMedicine, 2023. DOI 10.1016/j.eclinm.2023.102142. Reported by Vaping Post.

    A large randomised trial from a United States cancer centre, in which adults who smoke were given e-cigarettes without guidance, finding e-cigarettes effective as cessation aids. Cited in international coverage of the Malaysian debate.

    It is a United States trial of adults who already smoke, and it says nothing about people who never smoked or about long-term harm.

  4. Peer-reviewed study

    New Zealand’s accelerating smoking decline: lessons for tobacco harm reduction

    Beaglehole, Bonita and Youdan, The Lancet Regional Health: Western Pacific, 24 June 2026. DOI 10.1016/j.lanwpc.2026.101882. No conflicts of interest declared.

    Adult daily smoking in New Zealand fell from 15 per cent in 2015-16 to below 7 per cent by 2022-23, with the annual rate of decline increasing about five-fold after 2018-19. Youth vaping peaked in 2022 and fell after regulation. The authors conclude that regulated access to substantially less harmful nicotine products can complement demand and supply reduction and accelerate reductions in smoking.

    New Zealand data, a different population, a different enforcement environment and a different regulatory sequence from Malaysia’s. It is evidence that one regulated model coincided with a fast decline; it is not a forecast for Malaysia.

  • Systematic review: structured analysis of existing research to answer a specific question by identifying, evaluating and synthesising relevant studies
  • Living review: a systematic review that is continuously updated as new relevant research becomes available so that findings remain current
  • Peer review: experts in the same academic field evaluate a research study for its quality before it is published
  • Meta analysis: statistical method that combines results from multiple studies to produce an overall estimate of an effect or relationship
  • Randomised trial: scientific experiment that randomly assigns participants to different groups to study the effects of a medical treatment, drug or intervention

Three

Harm Reduction: Government and Expert Body Reviews

  1. Government review

    E-cigarettes: an evidence update

    Public Health England, published 19 August 2015, last updated 28 August 2015. Full report, PDF.

    The origin of the “around 95% less harmful than smoking” estimate. This figure is also often cited by MOVE in the conversation on vaping.

    The estimate is a contested one. It rested substantially on an expert elicitation exercise rather than on long-term outcome data. The elicitation was a 2014 multi-criteria decision analysis by Nutt and colleagues in European Addiction Research. The Lancet published an editorial questioning the review in August 2015. 

  2. Government review

    Nicotine vaping in England: 2022 evidence update

    Office for Health Improvement and Disparities, McNeill and others, 29 September 2022. Full report, PDF, 1,468 pages.

    The successor to the Public Health England 2015 review, it is more cautious in its language than the 2015 report, and considerably better evidenced. 

    While it does not reaffirm the 95% less harmful than smoking estimate, it does conclude that in the short and medium term, vaping poses a small fraction of the risks of smoking. This is also the argument for harm reduction, which is one of the key pillars of MOVE’s advocacy.

  3. Expert report

    Nicotine without smoke: tobacco harm reduction, and the 2024 evidence review

    Royal College of Physicians, 2016. Full report, PDF. The College’s page for that report displays a 2019 update date. The 2024 report is separately titled “E-cigarettes and harm reduction: an evidence review”, April 2024.

    A medical royal college’s position that e-cigarettes are substantially less harmful than combustible tobacco, with the 2024 review backing their use to help smokers stop. The 2016 report states that the hazard from long-term inhalation of vapour from the e-cigarettes available at the time “is unlikely to exceed 5% of the harm from smoking tobacco”. It carries weight because it comes from a body of physicians with no stake in the product.

    The 2024 report pairs its support for e-cigarettes as a cessation tool with a call to reduce their appeal, availability and affordability to people who do not smoke, including children and young people.

FOUR

Consumer and advocacy analysis

  1. White paper

    The subversion of public health: consumer perspectives

    Nancy E. Loucas, Coalition of Asia Pacific Tobacco Harm Reduction Advocates, October 2022. PDF, 512 KB, hosted here. Also on the publisher’s site.

    A regional consumer critique of World Health Organization positions on electronic nicotine delivery systems, written from the Asia Pacific. It is the clearest statement of the consumer-rights case in this region.

    Advocacy, and it reads as advocacy. CAPHRA argues a position MOVE broadly shares. Weigh it as argument, not as a finding.

  2. Fact sheet

    Why “youth epidemic” claims are misleading

    Arielle Selya PhD, Pinney Associates, for the Global Forum on Nicotine 2026, 4 June 2026.

    A challenge to how youth vaping figures are presented internationally, and to the way survey questions about ever-use get reported as regular use.

    International data, not Malaysian. The author’s affiliation, Pinney Associates, has consulted for tobacco and pharmaceutical clients. We know of no independent Malaysian study of youth uptake.

  3. Fact sheet

    Why “gateway to smoking and addiction” claims are misleading

    Arielle Selya PhD, Pinney Associates, for the Global Forum on Nicotine 2026, 4 June 2026.

    Addresses the claim that vaping leads young people into smoking, and the difficulty of separating a gateway effect from shared underlying risk factors.

    International data and not Malaysian. 

FIVE

Sources that argue against our advocacy

  1. Argues against MOVE

    An open letter to Malaysia’s Minister of Health

    SEATCA, signed by executive director E. Ulysses N. Dorotheo, 2 July 2026.

    SEATCA’s substantive 2026 policy demand, addressed to the minister: a comprehensive ban on the sale, production, distribution and use of e-cigarettes, heated tobacco products and other new nicotine products, expedited without further delay. It cites adolescent e-cigarette use rising from 9.8 per cent in 2017 to 14.9 per cent in 2022, an annual vaping-related healthcare cost of up to RM223.5 million, and more than 40 countries with bans, including eight ASEAN members. 

    Their argument echoes the Ministry of Health’s argument on the heavy burden of vaping-related healthcare costs and the rise of adolescent use.

  2. Argues against MOVE

    The Government’s decision to ban e-cigarettes reflects national urgency

    Galen Centre for Health and Social Policy, 11 September 2025.

    The clearest Malaysian statement of the case for prohibition, from a domestic health policy think tank.

    A policy position paper rather than new evidence. We answer it here.

  3. Cohort study Argues against MOVE

    Electronic cigarette use after smoking cessation and lung cancer risk

    Yeon Wook Kim and colleagues, Nature Medicine, June 2026. DOI 10.1038/s41591-026-04469-5.

    A retrospective cohort of about 4.5 million adults from South Korea’s National Health Screening Programme. Compared with people who quit smoking completely, e-cigarette use after cessation was associated with a higher incidence of lung cancer and with a higher rate of lung-cancer death. It is the most significant evidence against the harm reduction framing.

    It is observational, and the authors state that causality cannot be established. Its comparison group is people who quit nicotine altogether, not people who kept smoking, and outcomes for the vaping group remained better than for continued smoking. The journal page is paywalled and we read the findings from the Europe PMC record.

  4. Risk assessment Argues against MOVE

    The carcinogenicity of e-cigarettes: a qualitative risk assessment

    Bernard W. Stewart and colleagues, UNSW Sydney and others, Carcinogenesis, 2026, volume 47 issue 1. Reported by ScienceDaily, 21 June 2026.

    A qualitative assessment drawing on human biomarker studies, animal studies and mechanistic data, whose authors conclude that e-cigarettes are likely to cause lung cancer and oral cancer. It reached Malaysian consumer media in June 2026.

    The authors state their own limit: “Our assessment is qualitative and does not involve a numerical estimate of cancer risk or burden. We’ll only be able to determine the precise risk once longer-term studies are available.”

  5. Narrative review Argues against MOVE

    Vaping-related lung disease: a narrative review

    Mellor, Davidson and Pippard, Journal of Thoracic Disease, 16 June 2026. DOI 10.21037/jtd-2026-0515. Open access.

    A respiratory-medicine review grouping vaping-related lung disease as EVALI plus pneumothorax, hypersensitivity pneumonitis and bronchiolitis obliterans, and concluding that these devices are no longer viewed as safe. It is also the source for one of the few regulatory points that runs our way: the United Kingdom and the European Union have banned diacetyl and 2,3-pentanedione from e-liquids.

    A narrative review rather than a systematic one, and it does not weigh vaping against continued smoking, which is the comparison we base our argument on.

  6. Meta-analysis Argues against MOVE

    Risk of smoking relapse with the use of electronic cigarettes: A systematic review with meta-analysis of longitudinal studies

    Barufaldi and colleagues, Tobacco Prevention and Cessation, 2021. DOI 10.18332/tpc/132964. PMC8078138.

    Former smokers who used e-cigarettes had about twice the risk of relapsing to cigarettes compared with former smokers who did not: relative risk 2.03, 95 per cent confidence interval 1.39 to 2.96, falling to 1.38, 1.11 to 1.65, on the adjusted measures. Earlier versions of this website cited this paper on three pages as if it showed the opposite. We corrected those pages in September 2026 and list the paper here, among the sources that argue against us.

    Six studies, three in the quantitative synthesis, from the United States, the United Kingdom and France. It measures e-cigarette use as a risk factor for relapse in people who had already stopped everything. That is a different question from what happens to people currently vaping when a legal supply is withdrawn.

MOVE answers these criticisms, and others, on The case against us.

How to use this library

Please cite the original publishers. If you have spotted an error or if you have further questions and would like to engage with us, we can be reached through the media page.

To cite this page, you can also use the line below:

MOVE, Malaysian Organization of Vape Entity, "The evidence library", last reviewed 23 October 2026, move-malaysia.org/evidence-library.

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